Selank – COMPREHENSIVE RESEARCH PEPTIDE FOR NEUROPEPTIDE AND ANXIOLYTIC MECHANISM STUDIES

Scientific Overview of Selank

Selank is a synthetic heptapeptide analog of the endogenous immunomodulatory peptide tuftsin, developed to explore neuropeptide regulation, anxiolytic activity, and cognitive function modulation. It has been studied extensively for its role in neuromodulation, stress response, and peptide-based regulation of neurotransmitter systems.

In in-vitro and in-vivo studies, Selank has been investigated for its influence on:

• GABAergic System Modulation – analysis of Selank’s impact on GABA receptor expression and inhibitory neurotransmission balance (Andreeva et al., 2005)
• Anxiolytic and Cognitive Pathways – evaluation of behavioral and neurochemical effects related to anxiety reduction and cognitive enhancement (Ashmarin et al., 1998)
• Immunomodulatory Effects – exploration of Selank’s regulatory influence on cytokine production and immune–neuro interactions (Gudasheva et al., 2002)

Selank serves as a critical model compound in studies of neuropeptide signaling, stress physiology, and peptide-mediated neurotransmission. Its profile makes it valuable for ongoing research in neuropharmacology, psychoneuroimmunology, and molecular psychiatry.