Vial – IGF-1 LR3 1mg
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Name:IGF-1 LR3 (Long R3 Insulin-Like Growth Factor-1)
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Sequence:Modified IGF-1 Analog (83 Amino Acids with Arg³ Substitution and N-terminal Extension)
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Molecular Formula:C₉₉₀H₁₅₂₈N₂₆₂O₃₀₀S₇
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Molecular Weight:≈ 9200 Da
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CAS Registry Number:946870-92-4
IGF-1 LR3 – COMPREHENSIVE RESEARCH PEPTIDE FOR ANABOLIC AND CELLULAR GROWTH SIGNALING STUDIES
Scientific Overview of IGF-1 LR3
IGF-1 LR3 is a synthetic analog of insulin-like growth factor-1 (IGF-1) engineered with structural modifications that extend its half-life and reduce binding affinity to IGF-binding proteins, resulting in enhanced biological activity in research models.
In in-vitro and in-vivo studies, IGF-1 LR3 has been investigated for its effects on:
• IGF-1 Receptor Activation – analysis of receptor binding and downstream PI3K/AKT and mTOR signaling pathways (Le Roith et al., 2001)
• Cellular Growth and Proliferation – study of peptide-mediated effects on protein synthesis, cell differentiation, and anabolic signaling (Florini et al., 1996)
• Metabolic and Nutrient Signaling – investigation of glucose uptake, glycogen storage, and cellular nutrient partitioning mechanisms (Clemmons, 2007)
IGF-1 LR3 is widely utilized as a model compound in studies of growth factor biology, anabolic signaling, and receptor-mediated cellular regulation.
